What is anovulation?
Anovulation is a dishormonal disorder of the menstrual cycle and a mature egg cannot be separated from the ovary. Hormonal dependent changes in the uterus and inserts under the menstrual cycle are expressed in step-by-step steps, controlled by the central nervous system. Thanks to the menstrual cycle, a woman has the chance to become pregnant.
The normal menstrual cycle is 25-35 (most often 28) days, but a small number of women have physiological shortening or elongation of the cycle. In 75% of healthy women, the average duration of menstruation is 3-7 days, physiological blood loss does not exceed 50 ml.
In the menstrual period, all processes in the uterus are dependent on the ovarian hormones and the brain is controlled by the pituitary hypothalamus system. The menstrual cycle consists of ovarian and uterine cycles, respectively. In the ovaries, the egg matures and the uterus is responsible for the preparation of conditions for the development of a potential pregnancy.
Conditionally, the menstrual cycle is equally divided into two phases. The first stage is accompanied by ovarian formation of the follicle – a ur bubble ur with a shell where the egg matures and the follicle stimulates the ovarian hormone (FSH). The maturing follicle causes an increase in estrogen. Currently, the inner mucosa layer (endometrium) in the uterus is growing intensively – this is a form of preparation for a potential pregnancy. In the middle of the loop, the egg “grows” and the estrogen level drops and leads to the luteinizing hormone (LH) and progesterone. The change of hormonal effect leads to the fact that the follicle is destroyed and a mature egg leaves the ovary within an hour. The follicle is called ovulation when it goes beyond the ovule.
A mature egg maintains vitality and can be fertilized only two days. If this does not happen, he dies and begins to prepare for the elimination of unnecessary structural changes in the uterus – The overgrown endometrium is gradually rejected (second stage). Total rejection and extinction is called menstruation.
Full ovulation is a sign of normal two-phase menstruation cycle. In the absence of ovulation, the menstrual cycle becomes anovulatory.
An anovulation always points to a pathology. In healthy women, under the influence of adverse conditions throughout life, a single cycle of anovulation can occur, not leading to serious disturbances.
During the process of menstrual function, as in fading, the anovulation cycle is considered physiologically.
Anovulation almost always accompanies menstrual dysfunction and infertility.
Anovulation Treatments Therapy
Anovulation is not an independent disease because it is a symptom accompanying a significant number of gynecological disorders. It is not possible to eliminate anovulation without proper treatment of the underlying disease.
To successfully eliminate anovulation, you must first restore the normal rhythm of the menstruation. Sometimes, after a regular two-phase loop restoration, anovulation disappears. Unfortunately, most often the improved menstrual cycle remains anovulatory and the next stage of treatment is the hormonal stimulation of ovulation.
Regardless of the causes of anovulation, hormonal therapy is the most important. The choice of the drug always depends on which connection of the hormonal regulation.
Parallel to this, the correction of metabolic and endocrine disorders and elimination of psycho-emotional disorders, if necessary.
Stimulation of ovulation is a complex process with unpredictable results. Hormonal stimulating ovulation Clomifen has found wide application in the treatment of anovulation. In some cases, it is prescribed in combination with other hormonal agents.
Treatment of anovulation and treatment of infertility is not the same concept. After stimulation, the restoration of ovulation occurs in 70-90% of patients, but this does not guarantee the onset of pregnancy, only half is seen in cases. For the successful treatment of infertility, there is a need for a larger therapeutic program to eliminate hormonal and somatic causes and the stimulation of ovulation is the final stage.
If a woman wants to have a child, the hormonal stimulation of ovulation is justified. In all other cases it is important to correct only the normal rhythm of the menstruation.
Any hormonal treatment requires a careful personal approach, drugs are selected according to age, clinical findings, and survey data.
Physiological anovulation does not require treatment and is spontaneous.
Treatment of Polycystic Ovary Syndrome 2019
Polycystic Ovary Syndrome (PCOS) is a condition that causes ovulation in the ovaries and many small cysts and causes hormonal problems in women.
Although it is not known exactly why PCOS occurs, genetic factors are thought to be effective. Gynecologist, Dr. Hakan Özörnek stated that there may be a risk of PCOS if there are problems such as menstrual irregularities diabetes, high blood pressure.
WOMEN’S MOM WITH PCOS
Women with polycystic ovary syndrome are less likely to become pregnant than women without this syndrome. In women with PCOS, the main reason that makes it difficult to get pregnant is the lack of ovulation or irregular ovulation. These patients are often pregnant with assisted reproductive techniques.
Approximately 60-80% of women with PCOS are obese. Despite this carbohydrate metabolism disorder in PCOS, the issue of gestational diabetes was not clear in these patients. In obese pregnants, there is a greater risk of impaired glycemic control, hyperglycemia and insulin resistance. Obesity changes in carbohydrate metabolism In women, who have started to get pregnant and gain more weight during pregnancy, the likelihood of deterioration of carbohydrate tolerance is higher than normal weight pregnant women increase the probability of gestational diabetes (diabetes) during pregnancy.
Polycystic Ovary Syndrome (PCOS) Hair
Male type hair loss in polycystic ovary syndrome is the result of decreasing the amount of Hormone Binding
Globulin (SHBG) which increases the amount or sensitivity of hormones such as testosterone and androstenedione which is the raw material of dihydrotestosterone (DHT) hormone which is the most effective form of male hormones. It stands out.
Male pattern hair loss due to polycystic ovary syndrome usually shows slow progress. Sudden onset and rapid progression of hair loss is not very common in polycystic ovary syndrome. In case of sudden onset and rapid progression of hair loss, the ovarian or adrenal gland tumors should be considered first. In order to detect the tumor in this case, the ovaries should be examined by ultrasonography and the adrenal gland should be evaluated with other imaging methods.
Male type hair loss in polycystic ovary syndrome is usually associated with increased hair growth. However, it can also occur alone without another complaint.
Derec Increasing the amount or sensitivity of hormones such as testosterone, which is the raw material of dihydrotestosterone (DHT) hormone in Polycystic Ovary Syndrome and decreasing the amount of Sex Hormone Binding Globulin (SHBG) as well as the starting age, shedding rate and rate of shedding of familial (genetically) male hair loss. It affects.
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